Sofpironium bromide is an anticholinergic agent that has been studied for its use in treating primary axillary hyperhidrosis (PAH). It works by inhibiting M3 muscarinic receptors in the eccrine glands at the application site, thereby reducing sweating. The compound also demonstrates high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes.
- Anticholinergic agent
- Used in the study of primary axillary hyperhidrosis (PAH)
- Reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site
- Demonstrates high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes